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DT-810 Dissolution Tester

dissolution

JASCO offers the DT-810 Dissolution Tester, fully automated and designed for flexibility to provide dissolution testing of up to 8 samples with either the paddle method (standard) or the rotating basket method (optional).

Features

System Description

The DT-810 Dissolution Tester features a unique circular design that provides uniform water temperature while utilizing a round heating element. The Direct-Center ™ automatic centering mechanism provides hands-free positioning of the dissolution vessels and drive shafts for accurate dissolution tests with high reproducibility. All components are controlled via PC using simple keystroke operations with a user friendly graphic interface.

System Features

  • Meets USP, EP and JP requirements
  • 21 CFR Part 11 compliant
  • Excellent temperature stability using the circular bath
  • Uniform temperature distribution between vessels
  • Easy to set up and maintain
  • Direct-center vessel centering for automatic alignment of vessels and drive shafts
  • Test vessels manufactured with precise tolerances for vessel dimensions
  • PC control for monitoring
  • Automated tablet dropping system for dosage loading
  • Automatic sampling tube positioning for the upper and lower positions
  • Amber bath & vessels for light-sensitive samples

Dissolution Tester Specifications

 
Number of vessels 8 vessels, 1000 mL each
Spindles Test Method: Paddle method(Standard)
Rotation speed of spindle 5 to 300 rpm
Accuracy of rotation speed of spindle: ± 1 %
Thermostatted Bath Circular bath design with rotating function
Stirring: Magnetic stirrer
Temperature control: circular heating element
Temperature range: 32-45°C (25°C room temperature)
Temperature accuracy: ± 0.1°C (32-45°C)
Temperature stability: ± 0.05°C (32-45°C)
Temperature accuracy (dissolution vessels): ± 0.1°C (32-45°C)
Safety: Overheating protection using float switch, limit controller, temperature sensor
Drain port for quick and simple cleaning
Sample ports Automated lifting and lowering by stepping motor
User declared automatic sampling
Sampling position: automated by method parameters and solution volume
Table dropping Automatic (tablets, capsules, test sinker)
Vessel centering Direct-Center™automated mechanism
Temperature sensor position Vessel water bath, dissolution vessels (optional)
Power requirements 100,115, 200, 220, 230, 240 V; 50/60 Hz; 1100 VA (including LH-PV)
Dimensions 565(W) x 720(D) x 670(H) mm
Weight Approx. 90 Kg (main unit including vessels and paddles; without water)

Software specifications

Functions System control and monitoring, data collection, data analysis
Monitoring items DT-810: bath temperature, drive shaft rotation speed, sample flow, dissolution vessel temperature (optional)
Liquid handling unit: Autosampler position
Fraction collector: Current sample status
V-530: Absorbance value of specified cells

Liquid handling unit specifications

Model LH-PV2 LH-PV3
Number of sample lines 8
Solvent supply procedure 8-line peristaltic pump
Tubing PharMed&orig; tubing
Roller stepping motor, normal and reverse flow
Sampling Accuracy 3% (when sampling 20 mL)
Switching valve 2 valves 3 valves
Dimensions 160 (W) X 352 (D) X 311(H) mm 160 (W) X 352 (D) X 395 (H) mm
Weight 12 Kg 13 Kg

Fraction collector specifications

Model FC-812AS
Sampling procedure 8-nozzle filling mechanism
Sampling system Freely moving X, Y, Z axis positioning
Fraction collection 96 positions (20 mL test tubes)
Maximum sampling volume 20 mL
Minimum sampling interval Sequence: 4 minutes (parameter dependent)
Sampling: 1 minute for first sample, 2 minutes minimum thereafter (parameter dependent)
Contaminant free enclosure Supplies as standard
Power requirements 100,115, 200, 220, 230, 240 V; 50/60 Hz; 50 VA
Dimensions 300 (W) X 496 (D) X 415 (H) mm
Weight 23 Kg (main unit and sample rack)

8-position flow cell specifications

Model TQ-801
Cell(option) 8: 10 mm path length flow cells
5, 2 and 1 mm path length flow cells (optional)
Reference position single cell holder (100 mm cuvette)

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